By: James Pitt  Jul. 23, 2018

Fluid balance is a measure of whether a patient has excess, or insufficient, fluid relative to electrolytes. Fluid balance affects mortality in sepsis; early fluid administration saves lives, but later positive fluid balance is associated with higher mortality. According to the nonprofit Sepsis Alliance, sepsis is the leading cause of death in U.S. hospitals. However, it is challenging to assess how solutions to fluid imbalance will improve patient outcomes.

By: James Pitt  Jul. 20, 2018

Pressure ulcers are wounds that develop due to reduced blood flow, typically in patients who lie in the same position for long periods. Elderly and critically ill patients are at particular risk. A study based on 2006-2007 Medicare data found that patients with pressure ulcers are more likely to die in-hospital (odds ratio 2.81); have more than double the average length of stay; and are more likely to be readmitted within 30 days of discharge (odds ratio 1.33).

By: James Pitt  Jul. 19, 2018

Asthma and chronic obstructive pulmonary disease (COPD) are two of the most common lung disorders in the United States. Differential diagnosis can be a challenge. According to the American Academy of Family Physicians guidelines on distinguishing asthma from COPD, asthma generally has earlier onset, more variable symptoms, and normal chest X-ray. Many options for diagnosis and treatment are available, including recently developed digital health tools.

By: James Pitt  Jul. 18, 2018

Heart failure is the most common cause of death in the US, and the variety of treatments may seem intimidating. Even in a seemingly specific category like implants, options range from monitors to electric stimulators to total artificial hearts.

By: James Pitt  Jul. 12, 2018

Fluid overload is a common complication in severely ill patients. In a 2015 retrospective study of 63,000 patients, fluid imbalance increased average length of stay from 8 to 11.5 days. This included increasing average ICU length of stay from 3.6 to 6.2 days.

By: James Pitt  Jul. 09, 2018

Hospitals and physicians often struggle with how to evaluate the economic & quality benefits of WCDs. Hospitals & physicians face a number of challenges including:

1. What should be the appropriate measure that measures the quality & economic benefits of WCDs?

2. How does one get the data to measure the benefit?

3. Can we even get the right resources & teams to analyze the data?

By: James Pitt  Jul. 09, 2018

A Dexur analysis examined hospital-level data on intensive care unit stays among Medicare-eligible inpatients with COPD in South Carolina. Dexur has previously reported on how COPD complications raise hypertension readmission rates in South Carolina.

By: James Pitt  Jul. 06, 2018

Heart failure can be classified by ejection fraction. In heart failure with reduced ejection fraction (HFrEF, aka LVEF), the left ventricle pumps out an unusually low fraction of the blood that enters it. HFrEF has been a focus of research efforts, because most studies find it is associated with higher mortality than heart failure with preserved ejection fraction (HFpEF).

By: James Pitt  Jul. 05, 2018

Osteoporosis is a major cause of fractures in American women. A study in the March 2018 volume of Osteoporosis International found that hip fracture rates have plateaued at an unexpectedly high level from 2013-2015, leading to an excess of 11,000 hip fractures over projections based on continuing decline.

By: James Pitt  Jul. 04, 2018

Iron deficiency anemia (IDA) is a condition in which the body has too little iron to properly supply red blood cells, leading to fatigue and weakness. According to the Merck Manual, blood loss is the most common cause of IDA. About 70% of the body's iron is already in red blood cells, rather than stored in reserve, so patients may require iron supplementation after major blood loss.