Data Driven Disease Burden, Hospital & Healthcare News & Research


Disease Burden News, Research & Data Analysis


In Heart Failure

No Image

By: James Pitt  May. 23, 2018

Acute myocardial infarction (AMI) - also known as heart attack - is a major cause of mortality. Several antiplatelet drugs are commonly used for patients at risk of AMI. A randomized trial of 13,408 patients published in the Lancet finds acute coronary syndrome patients on ticagrelor had lower mortality than patients on clopidogrel. An observational study in France of 54,097 patients found that patients on ticagrelor had lower mortality and were less likely to have ICU stays than patients on clopidogrel.

Read more

In Sepsis

No Image

By: James Pitt  May. 22, 2018

Sepsis is a common and severe complication of infection. It is frequently comorbid with urinary tract infections (UTIs), a condition called urosepsis. A 2015 study of 5,272 sepsis cases in intensive care found that nearly 20% of cases stemmed from a urinary infection.

Read more

In Heart Failure

No Image

By: James Pitt  May. 21, 2018

Sudden cardiac arrest (SCA) is a major public health threat. According to the European Society of Cardiology, there are approximately 17 million cardiovascular disease patient deaths worldwide per year, 25% of which are caused by SCA.

Implantable cardiac defibrillators (ICDs) improve survival from SCA, but many patients are not candidates for ICD implant. One solution for these patients is a wearable cardiac defibrillator (WCD). The 2017 paper “Wearable cardioverter defibrillator: Bridge or alternative to implantation?” reviewed the use of WCDs.

Read more

Hospital & Physician News, Research & Data Analysis


Precision Medicine May Help Catch Idiopathic Pulmonary Fibrosis at Large Hospitals

No Image

By: James Pitt  May. 18, 2018

Interstitial lung disease (ILD) includes over 100 disorders with varying treatments and prognoses. Idiopathic pulmonary fibrosis (IPF) is according to the Cleveland Clinic the second most common ILD. IPF has a poor prognosis: “The majority of patients die of progressive fibrosing lung disease within 4 years of diagnosis.”

Read more

47% of 90-Day Fracture Readmissions in Women Involve Osteoporosis, Which Tymlos May Help Address

No Image

By: James Pitt  May. 17, 2018

Osteoporosis is a disease that weakens bones and increases the risk of fracture, particularly common in elderly women. First-line treatment is with anti-resorptive drugs like bisphosphonates. A 2017 Lancet study found that patient concerns about bisphosphonates’ side effects limit their use. The American Society for Bone and Mineral Research (ASBMR) recommends that patients on bisphosphonates with low fracture risk take “drug holidays” to decrease their risk of serious side effects.

Read more

Hyperkalemia Doubles Odds of ICU Stay Among Patients With Renal Failure With Complications at Large Tennessee Hospitals

No Image

By: James Pitt  May. 16, 2018

Hyperkalemia, an excess of blood potassium, is an electrolyte imbalance that is especially common in patients with heart failure or chronic kidney disease. Up to 6.35% of patients with HF or CKD have hyperkalemia. Dexur has previously reported on hyperkalemia and heart failure in Florida.

Read more