T2Biosystems’s Bacterial Panel Solution Could Help in Bacterial Sepsis Related Mortality

In Sepsis

By: Avinash Kumar  Jul. 01, 2019

Treating bloodstream infections earlier may prevent progression to sepsis, one of the leading causes of death in the U.S. According to T2Biosystems, for patients at risk of sepsis, rapid targeted treatment based on the identification of causative pathogens is critical because it is estimated that every hour of speeding up the time to targeted therapy decreases patient mortality by nearly 8%

Dexur analyzed Jan 2018 to Dec 2018 Medicare claims data to find out the In-hospital and 30 day mortality rate of Bacterial Sepsis for different hospitals across the United States. This analysis was done by considering diagnoses related to Bacterial species causing Sepsis as the primary diagnosis.

The 30 Day Mortality rate of all Sepsis DRGs with Bacterial Sepsis is at 15% in the United States. Within the Sepsis DRG group, DRG 870 (SEPTICEMIA OR SEVERE SEPSIS W MV 96+ HOURS) with Bacterial Sepsis has the highest 30 day mortality rate at 45%. DRG 871 (SEPTICEMIA OR SEVERE SEPSIS W/O MV 96+ HOURS W MCC) with Bacterial Sepsis has the most hospitalization and with a mortality rate of 18%.

Below is a list of selected hospitals and the mortality rates with Bacterial sepsis. 

RankHospital NameHospital CityHospital StateSepsis DRGs with Bacterial Sepsis - 30 Day Mortality RatesDRG 871 with Bacterial Sepsis - 30 Day Mortality RatesSepsis DRGs with Bacterial Sepsis - In Hospital Mortality RatesDRG 871 with Bacterial Sepsis - In Hospital Mortality Rates
1Mayo Clinic HospitalRochesterMN6%8%3%4%
2Cedars Sinai Medical CenterLos AngelesCA9%10%5%5%
3Memorial Hermann SouthwestHoustonTX16%16%6%6%
4Yale New Haven HospitalNew HavenCT19%22%8%9%
5Montefiore Medical CenterBronxNY21%19%18%16%

Mayo Clinic Hospital, Rochester and Cedars-Sinai Medical Center, Los Angeles have a lower 30 day mortality rate of Bacterial Sepsis with 6% and 9% respectively, which is less than the United States average of 15%. Memorial Hermann Health System of Houston, Yale New Haven Hospital, New Haven and Montefiore Medical Center has a higher than national 30 day mortality rate of 16%, 22% and 19% respectively.

The T2Bacteria Panel developed by T2Biosystems provides species identification in 3 to 5 hours whereas the other methods take 1 to 5 days or more. By incorporating the Panel as part of the sepsis bundle, physicians can get more patients on the right therapy faster, potentially preventing the progression of sepsis, while increasing the chances of both patient survival and recovery.

Dexur Pro members get access to:

Top 25 Hospitals and Mortality Rates with Highest volume of Bacterial Sepsis Hospitalizations


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Avinash Kumar

Avinash Kumar is a Business analyst with over 9 years of healthcare experience. He has expertise in Real World Evidence (RWE), healthcare claims analytics, market research, data analytics, benefits configuration, claim contractual reprising, adjudication, implementation of reimbursement rule edits for healthcare payers and revenue cycle management for providers. Avinash holds a Master's degree in Operations management and life sciences. He is a certified medical coder from American Association of Professional Coders (AAPC).